Pupillary dilation velocity is reduced in intensive care unit patients with septic shock
Main finding · PLRdil.vel.Result — go to the resultDifference −0.3 mm/s 95% CI −0.4 to −0.2Authors' conclusion
Septic shock may be associated with changes in sympathetic autonomic tone which is supported by the findings from this study that septic shock was associated with a slower dilation velocity in the pupillary light reflex.
Study context
- Population
- Adults acutely admitted to a mixed intensive care unit (ICU)
- Participants
- 91 participants
- Exposure
- Septic shock vs no septic shock
- Septic shockn = 35
- Outcome
- Dilation velocity of the pupillary light response (PLRdil.vel.), measured with a portable pupillometer twice daily
Methodological detailssingle-centre
- Single-centre
Main finding
PLRdil.vel.
Difference
−0.3 mm/s
95% CI −0.4 to −0.2
Septic shock vs No septic shock
difference −0.3 mm/s (95% CI −0.4 to −0.2)
As reported in the abstract
Observational data: associations, not effects.
Original publication
Pupillary dilation velocity is reduced in intensive care unit patients with septic shock. Acta Anaesthesiol Scand. Published 18 September 2023. doi:10.
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