Perioperative medicine & outcomes

Quality of Recovery after Spinal or General Anesthesia for Total Knee Arthroplasty: a retrospective study

Anaesth Crit Care Pain MedPublished Retrospective cohort study

Authors' conclusion

Spinal anesthesia was associated with better early postoperative quality of recovery at POD 3 after TKA compared to general anesthesia.

Study context

Population
Adults undergoing primary Total Knee Arthroplasty (TKA), Strasbourg University Hospital, France, March 2020–June 2023, prospectively followed with mQoR-15Fanalysed
Participants
447 adults
Exposure
Spinal vs general anaesthesia for primary TKA
  • Spinal anesthesia (SA)n = 178
  • General anesthesia (GA)n = 269reference
Outcome
Difference in mean mQoR-15F score
Follow-up
POD 1, 3, 14, and 28
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Mean mQoR-15F score · POD 3

SA

122.6

mean

GA

115.9

mean

P < 0.01

Observational data: associations, not effects.

Secondary outcomes

mQoR-15F subscales · postoperative days (POD) 3

SA associated with improved pain, physical comfort, autonomy and psychological dimensions

Operating room occupancy

Shorter with SA

Hospital LOS and 28-day mortality

No differences

Safety

PONV

No difference

Original publication

Quality of Recovery after Spinal or General Anesthesia for Total Knee Arthroplasty: a retrospective study. Anaesth Crit Care Pain Med. Published 24 September 2026. doi:10.1016/j.accpm.2026.101905

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