Pediatric anesthesia & critical care
Quantifying Procedure-level Prophylaxis Misutilization in Pediatric Surgery: Implications for the Prioritization of Antimicrobial Stewardship Efforts
Study context
- Population
- Children undergoing elective surgical procedures at 52 children's hospitals, October 2015 to December 2019
- Participants
- 56,845 cases
- Outcome
- Procedure-level compliance with consensus guidelines for prophylaxis utilization (indication, antimicrobial spectrum, duration)
Methodological detailsmulticentre, Pediatric Health Information System database
- Multicentre
- Pediatric Health Information System database
Main finding
As reported in the abstract
Inappropriate antimicrobial prophylaxis utilization
Overall inappropriate utilization rate
56%
Noncompliance due to unindicated utilization
43%
Noncompliance due to prolonged duration
32%
Noncompliance due to excessively broad-spectrum agents
25%
Observational data: associations, not effects.
Further findings
Procedures with greatest relative contribution to noncompliant cases
- Unindicated utilization: cholecystectomy, inguinal and umbilical hernia repair (share of all cases)
- 63.2%
- Excessively broad-spectrum agents: small bowel resections, gastrostomy, colorectal procedures
- 70.1%
- Prolonged duration: pectus excavatum repair, small and large bowel procedures
- 57.6%
- More than half of all noncompliant cases associated with 5 procedures (cholecystectomy, small bowel procedures, inguinal hernia repair, gastrostomy, pectus excavatum)
Original publication
Quantifying Procedure-level Prophylaxis Misutilization in Pediatric Surgery: Implications for the Prioritization of Antimicrobial Stewardship Efforts. Ann Surg. Published 7 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →