Neuroanesthesia & neurocritical care

Quantitative regional cerebral blood flow measurement using near-infrared spectroscopy and indocyanine green in patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya disease: a novel method using a frequency filter

J Clin Monit ComputPublished Method validation study

Authors' conclusion

rCBF measurements based on this novel method were weakly correlated with rCBF measurements with SPECT.

Study context

Population
Patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya diseaseprocedures analysed
Participants
34 patients
Comparison
Regional cerebral blood flow (rCBF) by near-infrared spectroscopy (NIRS) with indocyanine green (ICG) and frequency filter vs SPECT
Outcome
Agreement between rCBF_N and rCBF_S (ICC3)

Performance

As reported in the abstract

Agreement rCBF_N vs rCBF_S (ICC3)

ICC3, diseased side (weak); 95% CI −0.03-0.5; p = 0.07

0.25

ICC3, non-diseased side (weak); 95% CI −0.05-0.5; p = 0.08

0.24

Further findings

rCBF_N (NIRS) change from baseline to end of surgery

MD (ml/min/100 g) (95% CI)
Diseased side2.99 (0.40–5.57)
Non-diseased side4.94 (2.35–7.52)

rCBF_S (SPECT) change

MD (ml/min/100 g) (95% CI)
Diseased side3.98 (2.30–5.67)
Non-diseased side2.77 (1.09–4.45)

rCBF_N (NIRS) change from baseline to end of surgery

rCBF_N increased from baseline to end of the surgery

rCBF_S (SPECT) change

Similar trends observed for rCBF_S

Original publication

Quantitative regional cerebral blood flow measurement using near-infrared spectroscopy and indocyanine green in patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya disease: a novel method using a frequency filter. J Clin Monit Comput. Published 27 September 2022. doi:10.1007/s10877-022-00916-z

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