Neuroanesthesia & neurocritical care
Quantitative regional cerebral blood flow measurement using near-infrared spectroscopy and indocyanine green in patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya disease: a novel method using a frequency filter
Authors' conclusion
rCBF measurements based on this novel method were weakly correlated with rCBF measurements with SPECT.
Study context
- Population
- Patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya diseaseprocedures analysed
- Participants
- 34 patients
- Comparison
- Regional cerebral blood flow (rCBF) by near-infrared spectroscopy (NIRS) with indocyanine green (ICG) and frequency filter vs SPECT
- Outcome
- Agreement between rCBF_N and rCBF_S (ICC3)
Performance
As reported in the abstract
Agreement rCBF_N vs rCBF_S (ICC3)
ICC3, diseased side (weak); 95% CI −0.03-0.5; p = 0.07
0.25
ICC3, non-diseased side (weak); 95% CI −0.05-0.5; p = 0.08
0.24
Further findings
rCBF_N (NIRS) change from baseline to end of surgery
| MD (ml/min/100 g) (95% CI) | ||
|---|---|---|
| Diseased side | 2.99 (0.40–5.57) | |
| Non-diseased side | 4.94 (2.35–7.52) | |
| −50510Difference, ml/min/100 g (linear scale) |
rCBF_S (SPECT) change
| MD (ml/min/100 g) (95% CI) | ||
|---|---|---|
| Diseased side | 3.98 (2.30–5.67) | |
| Non-diseased side | 2.77 (1.09–4.45) | |
| −50510Difference, ml/min/100 g (linear scale) |
rCBF_N (NIRS) change from baseline to end of surgery
- rCBF_N increased from baseline to end of the surgery
rCBF_S (SPECT) change
- Similar trends observed for rCBF_S
Original publication
Quantitative regional cerebral blood flow measurement using near-infrared spectroscopy and indocyanine green in patients undergoing superficial temporal to middle cerebral artery bypass for moyamoya disease: a novel method using a frequency filter. J Clin Monit Comput. Published 27 September 2022. doi:10. 1007/ s10877-022-00916-z
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