Perioperative medicine & outcomes
Real-world outcomes of the hypotension prediction index in the management of intraoperative hypotension during non-cardiac surgery: a retrospective clinical study
Authors' conclusion
The HPI combined with a GDFT protocol may help to minimize the severity of IOH during non-cardiac surgery.
Study context
- Population
- Consecutive adults undergoing urgent or elective non-cardiac surgery with moderate-to-high bleeding risk, requiring invasive BP and continuous CO monitoring
- Participants
- 104 adults
- Exposure
- Goal-directed fluid therapy (GDFT) supported by HPI vs GDFT alone
- HPIn = 52
- GDFTn = 52reference
- Outcome
- Time-weighted average of hypotension for MAP < 65 mmHg (TWAMAP<65)
Methodological detailssingle-centre, blinded outcome revision, Non-parametric tests with Hodges-Lehmann estimator, Outcomes downloaded from medical records and revised by clinicians blinded to management
- Single-centre
- Blinded outcome revision
- Non-parametric tests with Hodges-Lehmann estimator
- Outcomes downloaded from medical records and revised by clinicians blinded to management
Main finding
As reported in the abstract
P = 0.037
Observational data: associations, not effects.
Further findings
| Outcome | HPI | GDFT | Median difference (days) | P value |
|---|---|---|---|---|
| Postoperative complications | 0.46 ± 0.98 | 0.88 ± 1.20 | P = 0.035 | |
| Hospital LOSSignificantly shorter with HPI | 2 | P = 0.019 | ||
| Blood loss | P = 0.279 |
Blood loss
- Comparable
Original publication
Real-world outcomes of the hypotension prediction index in the management of intraoperative hypotension during non-cardiac surgery: a retrospective clinical study. J Clin Monit Comput. Published 2 June 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →