ICU sedation, delirium & recovery
Recurrent delirium episodes within the intensive care unit: Incidence and associated factors
Authors' conclusion
Over 10% of delirious ICU patients had recurrent symptoms. Factors associated with recurrence included age, duration of mechanical ventilation and medication exposure.
Study context
- Population
- Intensive care unit (ICU) patients diagnosed with deliriumICU admissions with delirium
- Participants
- 8,591 patients
- Outcome
- Recurrent delirium (any positive delirium assessment after clearance, i.e. 48 h of negative assessments following initial episode)
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Main finding
As reported in the abstract
Incidence of recurrent delirium
Recurrent delirium
1067
12.4%
Observational data: associations, not effects.
Further findings
Factors associated with increased odds of recurrent delirium
| OR (95% CI) | ||
|---|---|---|
| ShockAdjusted for pre-defined covariates | 1.45 (1.20–1.75) | |
| Increased duration of mechanical ventilationAdjusted for pre-defined covariates | 2.43 (2.22–2.65) | |
| Propofol useAdjusted for pre-defined covariates | 1.35 (1.02–1.80) | |
| HaloperidolAdjusted for pre-defined covariates | 1.53 (1.26–1.86) | |
| QuetiapineAdjusted for pre-defined covariates | 2.45 (1.98–3.02) | |
| OlanzapineAdjusted for pre-defined covariates | 1.54 (1.25–1.88) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | OR (95% CI) | |
|---|---|---|
| Factors associated with increased odds of recurrent deliriumMedical ICU vs Cardiovascular ICU · adjusted for pre-defined covariates | 3.25 (2.42–4.37) | |
| Factors associated with increased odds of recurrent deliriumSurgical ICU vs Cardiovascular ICU · adjusted for pre-defined covariates | 3.00 (2.21–4.06) | |
| Factors associated with increased odds of recurrent deliriumTrauma ICU vs Cardiovascular ICU · adjusted for pre-defined covariates | 2.17 (1.58–3.00) | |
| 0.20.5125Odds ratio (log scale) |
- Factors associated with increased odds of recurrent delirium — Age (nonlinear)
- p = 0.02
Original publication
Recurrent delirium episodes within the intensive care unit: Incidence and associated factors. J Crit Care. Published 23 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →