Cardiothoracic & vascular anesthesia

Regional Anesthesia Combined With Respiratory Physiotherapy Improves Postoperative PaO₂:FiO₂ Ratio and Pulmonary Atelectasis in Thoracolaparoscopic Esophagectomy:A Randomized Controlled Trial

J Cardiothorac Vasc AnesthPublished Randomised controlled trial

Authors' conclusion

Regional anesthesia combined with respiratory physiotherapy significantly improved the PaO₂:FiO₂ ratio, reduced pulmonary atelectasis, and accelerated postoperative recovery after thoracolaparoscopic esophagectomy.

Study context

Population
Patients with esophageal cancer scheduled for elective thoracolaparoscopic esophagectomy, tertiary hospital
Participants
81 patients
Comparison
C vs N vs ND
Primary endpoint
PaO₂:FiO₂ ratio
Methodological detailsthree-arm
  • Three-arm

Primary result

As reported in the abstract

24 hours postoperatively
Significantly higher in the ND group than in both C and N
p < 0.05

Secondary outcomes

Pulmonary atelectasis — ND vs N and C

P < 0.01

Overall lung ultrasound scores · 1 and 24 hours postoperatively

Significantly lower in ND than in C and N
P < 0.05

Hospital LOS

Shortest in ND among the 3 groups
P < 0.05

Safety

Respiratory failure and unplanned reintubation

Lowest rates in ND vs the other 2 groups
P < 0.05

Original publication

Regional Anesthesia Combined With Respiratory Physiotherapy Improves Postoperative PaO₂:FiO₂ Ratio and Pulmonary Atelectasis in Thoracolaparoscopic Esophagectomy:A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. Published 30 January 2026. doi:10.1053/j.jvca.2026.01.039

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