Cardiothoracic & vascular anesthesia

Regional Anesthesia for Lobectomy and Risk of Pulmonary Complications: A National Safety Quality Improvement Program Propensity-Matching Analysis

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

The RA techniques were not associated with a lower incidence of pulmonary complications in lobectomy surgery.

Study context

Population
Adults undergoing lobectomy by video-assisted thoracoscopic surgery (VATS) or open thoracotomy, ACS NSQIP, 2014–20174,134 VATS
Exposure
General anesthesia (GA) plus regional anesthetic (RA) vs GA alone
Outcome
Composite postoperative pulmonary complication (PPC):
  • Pneumonia
  • Reintubation
  • Failure to wean from the ventilator
Methodological detailspropensity-matched, national registry (ACS NSQIP)
  • Propensity-matched
  • National registry (ACS NSQIP)

Main finding

As reported in the abstract

Composite PPC by surgical approach (subgroup)
RA+GA vs GAOdds ratio (95% CI)P value
VATS (2,067 vs 2,067)
1.07(0.81–1.43)
P = 0.622
Thoracotomy (1,556 vs 1,556)
1.19(0.93–1.51)
P = 0.174

Observational data: associations, not effects.

Further findings

Readmission, LOS and mortality · 30 days

No statistically significant difference between groups

Original publication

Regional Anesthesia for Lobectomy and Risk of Pulmonary Complications: A National Safety Quality Improvement Program Propensity-Matching Analysis. J Cardiothorac Vasc Anesth. Published 11 December 2022. doi:10.1053/j.jvca.2022.12.005

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