ICU sedation, delirium & recovery

Relatives’ experiences of end-of-life care and organ donation after controlled circulatory death: a national prospective multicenter study

Crit CarePublished Prospective cohort study

Authors' conclusion

Relatives of potential cDCDD donors experience high levels of psychological distress, but OD discussions did not exacerbate burden.

Study context

Population
Relatives of patients identified as potential cDCDD donors after a decision to withdraw life-sustaining measures (WLSM), 32 French ICUs118 followed up at 3 months
Participants
159 relatives
Exposure
Organ donation (OD)+ vs OD-
  • OD+n = 119
  • OD-n = 40reference
Outcome
PTSD symptoms (IES-R)
Follow-up
3 and 6 months
Methodological detailsmulticentre, national, Follow-up completed in 109 relatives at 6 months
  • Multicentre
  • National
  • Follow-up completed in 109 relatives at 6 months

Main finding

As reported in the abstract

3 months
  • PTSD symptoms reported by one third of relatives
  • Psychological outcomes did not differ between OD+ and OD-

Observational data: associations, not effects.

Further findings

Anxiety and depression (HADS) · 3 months

Half reported anxiety and one third depression, persisting at 6 months for a substantial proportion

Distressing experience of dying and death (CAESAR)

Around 10% described a distressing experience

Prolonged grief disorder (prolonged grief (PG-13))

Fewer than 10% met criteria

Perception of being asked to authorize donation

Perceived being asked to authorize donation, though most felt involved in WLSM and OD discussions
80%

Original publication

Relatives’ experiences of end-of-life care and organ donation after controlled circulatory death: a national prospective multicenter study. Crit Care. Published 21 December 2025. doi:10.1186/s13054-025-05807-8

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