Perioperative medicine & outcomes
Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study
Authors' conclusion
The reliability of proxy assessment with the instruments used was insufficient, exhibiting a significant bias in the pre-admission status of ICU patients
Study context
- Population
- Surgical adults able to answer PROMs (SF-36, EQ-5D-5L, WHODAS 2.0, IADL, Barthel Index) independently, with a proxy available, Germany
- Participants
- 204 patient-proxy pairs
- Exposure
- Proxy vs patient assessment of pre-admission status via PROMs
- ICUn = 102
- Outcome
- Reliability of proxy assessment of pre-ICU admission status (Bland-Altman plots, Cohen's kappa)
Methodological detailsmulticentre, two tertiary care university hospitals, Patients interviewed preoperatively; proxies interviewed postoperatively in the ICU or normal ward, Median patient and proxy age 69 and 64 years; 41% and 68% female
- Multicentre
- Two tertiary care university hospitals
- Patients interviewed preoperatively; proxies interviewed postoperatively in the ICU or normal ward
- Median patient and proxy age 69 and 64 years; 41% and 68% female
Main finding
As reported in the abstract
Proportion of pairs with within-pair difference outside the MCID
| Group | Value | SF-36 MCS | WHODAS 2.0 | EQ-5D-5L | Barthel-Index |
|---|---|---|---|---|---|
| Normal ward | 46% | 59 (58%) | 58 (57%) | 40 (39%) | 22 (22%) |
| ICU | 57% | 62 (61%) | 78 (77%) | 46 (45%) | 21 (21%) |
Value
Normal ward46%
ICU57%
SF-36 MCS
Normal ward59 (58%)
ICU62 (61%)
WHODAS 2.0
Normal ward58 (57%)
ICU78 (77%)
EQ-5D-5L
Normal ward40 (39%)
ICU46 (45%)
Barthel-Index
Normal ward22 (22%)
ICU21 (21%)
Observational data: associations, not effects.
Original publication
Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study. Crit Care. Published 19 May 2025. doi:10. 1186/ s13054-025-05431-6
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