Perioperative medicine & outcomes

Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study

Crit CarePublished Prospective observational study

Authors' conclusion

The reliability of proxy assessment with the instruments used was insufficient, exhibiting a significant bias in the pre-admission status of ICU patients

Study context

Population
Surgical adults able to answer PROMs (SF-36, EQ-5D-5L, WHODAS 2.0, IADL, Barthel Index) independently, with a proxy available, Germany
Participants
204 patient-proxy pairs
Exposure
Proxy vs patient assessment of pre-admission status via PROMs
  • ICUn = 102
Outcome
Reliability of proxy assessment of pre-ICU admission status (Bland-Altman plots, Cohen's kappa)
Methodological detailsmulticentre, two tertiary care university hospitals, Patients interviewed preoperatively; proxies interviewed postoperatively in the ICU or normal ward, Median patient and proxy age 69 and 64 years; 41% and 68% female
  • Multicentre
  • Two tertiary care university hospitals
  • Patients interviewed preoperatively; proxies interviewed postoperatively in the ICU or normal ward
  • Median patient and proxy age 69 and 64 years; 41% and 68% female

Main finding

As reported in the abstract

Proportion of pairs with within-pair difference outside the MCID
GroupValueSF-36 MCSWHODAS 2.0EQ-5D-5LBarthel-Index
Normal ward46%59 (58%)58 (57%)40 (39%)22 (22%)
ICU57%62 (61%)78 (77%)46 (45%)21 (21%)

Value

Normal ward46%
ICU57%

SF-36 MCS

Normal ward59 (58%)
ICU62 (61%)

WHODAS 2.0

Normal ward58 (57%)
ICU78 (77%)

EQ-5D-5L

Normal ward40 (39%)
ICU46 (45%)

Barthel-Index

Normal ward22 (22%)
ICU21 (21%)

Observational data: associations, not effects.

Original publication

Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study. Crit Care. Published 19 May 2025. doi:10.1186/s13054-025-05431-6

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