Residual neuromuscular block in the postanaesthesia care unit: a single-centre prospective observational study and systematic review
Authors' conclusion
The incidence of residual neuromuscular block in the PACU was 2.2%.
Study context
- Population
- Surgical patients in a large Dutch teaching hospital with readily available quantitative neuromuscular transmission (NMT) monitoring and reversal agents
- Participants
- 500 patients
- Outcome
- RNMB in the PACU (TOFR <0.9 by acceleromyography on arrival)
Methodological detailssingle-centre, Anaesthetic technique and intraoperative NMT monitoring independently chosen by the attending anaesthesiologist
- Single-centre
- Anaesthetic technique and intraoperative NMT monitoring independently chosen by the attending anaesthesiologist
Pooled result
As reported in the abstract
Incidence of RNMB (TOFR <0.9) in the PACU
Patients with train-of-four ratio (TOFR) <0.9
11
2.2%
Further pooled results
Automatically recorded TOFR ≥0.9 at end of surgery · the only difference
P = 0.009
Intraoperative NMT monitoring and reversal
- Intraoperative NMT monitoring performed
- 77.6%
- Sugammadex administered
- 38%
- Neostigmine administered
- 0
Residual neuromuscular block (RNMB) incidence since 2000 (systematic review)
- Range of reported incidences
- 3.5% to 53.3%
- Decreasing trend in Europe and North America
Original publication
Residual neuromuscular block in the postanaesthesia care unit: a single-centre prospective observational study and systematic review. Br J Anaesth. Published 23 October 2024. doi:10.
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