Respiratory failure & ventilation
Respiratory rate measurement by pressure variation in the high flow nasal cannula-system in healthy volunteers
Authors' conclusion
The pressure variation in the HFNC system allows for respiratory rate and effort monitoring, but requires further development to increase precision.
Study context
- Population
- Healthy volunteers breathing regularly, quickly and slowly on modified HFNC system
- Participants
- 25 volunteers
- Comparison
- Pressure-based respiratory rate count in HFNC system vs count by observation
- Outcome
- Agreement of respiratory rate counted from pressure variation vs observation
Main finding
As reported in the abstract
Agreement of pressure-based vs observed respiratory rate (95% Limits of Agreement)
| Group | 95% Limits of Agreement |
|---|---|
| 30 l/min -closed mouth | - 1.85;1.91 |
| 70 l/min - closed mouth | −2.25;2.47 |
| 70 l/min - open mouth | −30.32;19.93 |
95% Limits of Agreement
30 l/min -closed mouth- 1.85;1.91
70 l/min - closed mouth−2.25;2.47
70 l/min - open mouth−30.32;19.93
Further findings
| Outcome | 30 l/min - open mouth | 70 l/min - open mouth |
|---|---|---|
| False detection of apnea in pressure-based measurements | 10% | 11% |
False detection of apnea in pressure-based measurements
- Not with a closed mouth
Correlation of pressure difference with respiratory effort
- Correlation present, except for 30 l/min with open mouth
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Respiratory rate measurement by pressure variation in the high flow nasal cannula-system in healthy volunteers. J Clin Monit Comput. Published 12 June 2024. doi:10.
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