Obstetric anaesthesia

Respiratory Variation Index as a marker of labour pain intensity with epidural analgesia: a pilot exploratory study

Int J Obstet AnesthPublished Prospective observational study

Authors' conclusion

Respiratory Variation Index exhibits optimal diagnostic performance for stratifying moderate-to-severe or severe uterine contraction pain

Study context

Population
Labouring women with epidural analgesia
Participants
21 women · 137 contraction episodes
Outcome
Discrimination of moderate-to-severe from no-to-mild uterine contraction pain (NRS)
Methodological detailspilot exploratory
  • Pilot exploratory

Main finding

As reported in the abstract

Discrimination of moderate-to-severe and severe uterine contraction pain

Respiratory rate variability independently associated with moderate-to-severe pain, OR

1.193

95% CI 1.100–1.293, β = 0.176, P < 0.001

Respiratory amplitude variability independently associated with moderate-to-severe pain, OR

1.067

95% CI 1.031–1.122, β = 0.073, P = 0.001

Respiratory Variation Index AUC for moderate-to-severe pain

0.853

95% CI 0.785–0.922, P < 0.001

Respiratory Variation Index AUC for severe pain

0.748

95% CI 0.665–0.831, P < 0.001

Observational data: associations, not effects.

Original publication

Respiratory Variation Index as a marker of labour pain intensity with epidural analgesia: a pilot exploratory study. Int J Obstet Anesth. Published 1 July 2026. doi:10.1016/j.ijoa.2026.105232

Composed by AI from the published abstract and checked against it. How Briefs are made →

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