Pediatric anesthesia & critical care
Retrospective Cohort Study of Perioperative Complications in Symptomatic and Asymptomatic Children Testing SARS‐CoV‐2‐Positive Within 21 Days Before Surgery
Authors' conclusion
Preoperative symptoms, especially of the lower respiratory tract, increased the risk for perioperative complications in children diagnosed with COVID-19 within 10 days of surgery.
Study context
- Population
- Children < 18 years undergoing surgery with GA who tested COVID-19+ ≤ 10 days (primary) or ≤ 21 days (secondary) before anesthesia, March 1, 2020 to March 1, 2022225 analysed (primary)
- Exposure
- Symptomatic vs asymptomatic COVID-19+ children; upper vs lower respiratory symptoms
- Outcome
- Perioperative complications (postoperative respiratory complications, postoperative medications, postoperative oxygen support)
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Odds ratio (CI)P value
Symptomatic vs Asymptomaticpostoperative respiratory complications
3.53(1.18–10.6)
P = 0.024Symptomatic vs Asymptomaticpostoperative medications
7.64(2.29–25.51)
P = 0.001Symptomatic vs Asymptomaticpostoperative oxygen support
2.62(1.19–5.79)
P = 0.017Upper respiratory symptoms vs Lower respiratory symptomspostoperative medications
0.1(0.01–0.89)
P = 0.039Upper respiratory symptoms vs Lower respiratory symptomspostoperative oxygen support
0.08(0.01–0.45)
P = 0.004Observational data: associations, not effects.
Secondary outcomes
Outcomes by COVID-19+ test < 6 days before anesthesia vs other groups (≤ 21 days cohort)
- Longer PACU stays
- P < 0.001
- More postoperative respiratory complications
- P = 0.001
- More medication use
- P = 0.038
- More oxygen use
- P = 0.002
- Additional 298 patients analysed
- Analysis of variance
Original publication
Retrospective Cohort Study of Perioperative Complications in Symptomatic and Asymptomatic Children Testing SARS‐CoV‐2‐Positive Within 21 Days Before Surgery. Paediatr Anaesth. Published 5 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →