Perioperative medicine & outcomes

Risk-Adjustment of Perioperative Mortality Rate Measurement in a Low-Income Country

Anesth AnalgPublished Observational cohort study

Authors' conclusion

Laparotomy had a strong independent association with mortality at a Ugandan secondary hospital.

Study context

Population
Surgical operations at a Ugandan secondary referral hospital
Participants
7,170 operations
Outcome
In-hospital perioperative mortality
Follow-up
30 days
Methodological detailssingle-centre, 42-month
  • Single-centre
  • 42-month

Main finding

As reported in the abstract

30-day perioperative mortality rate
30-day perioperative mortality rate (381/7170)
5.3 %
Laparotomy, aOR (95% CI 1.6, 4.3), P < .001 (procedure P < .001)
2.6
Cranial surgery, aOR (95% CI 1.6, 4.9), P < .001
2.8
American Society of Anesthesiologists (ASA) rating, aOR (95% CI 2.6, 3.6), P < .001
3.1
HIV positive, aOR (95% CI 1.5, 4.8), P < .001 (HIV serostatus P < .001)
2.7
Urgent/emergent procedure, aOR (95% CI 1.2, 2.3), P = .003
1.7
Distant referral home district, aOR (95% CI 1.0, 1.9), P = .027 (home district P = .015)
1.4
Age decile, aOR (95% CI 1.0,1.2), P = .001
1.1

Observational data: associations, not effects.

Further findings

Laparotomy share of procedures and deaths

Laparotomy procedures (commonest)
2361
Deaths associated with laparotomy (216/381)
56.3%

Original publication

Risk-Adjustment of Perioperative Mortality Rate Measurement in a Low-Income Country. Anesth Analg. Published 14 November 2025. doi:10.1213/ane.0000000000007475

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