Pediatric anesthesia & critical care
Risk Analytics Clinical Decision Support Decreases Duration of Vasoactive Infusions Following Pediatric Cardiac Surgery: A Multicenter Before and After Clinical Trial
Main finding · Vasoactive infusion durationResult — go to the resultShorter duration (risk-adjusted negative binomial regression) 29% 95% CI 14–42%Authors' conclusion
A CDSS informed by ID o2 significantly decreased vasoactive infusions duration. There was no discernible change in ICU LOS, CA rate, or weaning failure rate.
Study context
- Population
- Infants >36 weeks estimated gestational age and 2 kg after cardiac surgery with CPB, treated with inotropes and vasoactive infusions (IVAI) ≥6 hours, 3 pediatric cardiac ICUs (CICUs)
- Participants
- 343 vs 432
- Comparison
- Clinical decision support system (CDSS) informed by IDo2 vs control
- Interventionn = 343
- Controln = 432reference
- Outcome
- IVAI duration
Methodological detailsmulticentre
- Multicentre
Main finding
Vasoactive infusion duration
Shorter duration (risk-adjusted negative binomial regression)
29%
95% CI 14–42%
P < 0.01
As reported in the abstract
Secondary outcomes
CICU length of stay (LOS), cardiac arrest (CA) rate, IVAI weaning failure
- No significant trends observed
Original publication
Risk Analytics Clinical Decision Support Decreases Duration of Vasoactive Infusions Following Pediatric Cardiac Surgery: A Multicenter Before and After Clinical Trial. Crit Care Med. Published 29 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →