Hemodynamics, fluids & transfusion

Risk factors for a central-to-peripheral arterial blood pressure gradient in adults: a systematic review

Can J AnaesthPublished Systematic review

Authors' conclusion

The present systematic review identified numerous risk factors for CPAPGs.

Study context

Population
Adults with simultaneous radial and central arterial pressure monitoring (CPB, hepatic transplant, intensive care unit (ICU) stay and other settings)
Participants
5,598 adults · 55 studies
Outcome
Risk factors for central-to-peripheral arterial BP gradients (CPAPGs) and their level of consensus
Methodological detailsSearched MEDLINE/PubMed, Embase, Cochrane (CENTRAL, Database of Systematic Reviews) from inception to 15 July 2024; 741 articles retrieved
  • Searched MEDLINE/PubMed, Embase, Cochrane (CENTRAL, Database of Systematic Reviews) from inception to 15 July 2024; 741 articles retrieved

Pooled result

As reported in the abstract

Risk factors for CPAPGs

Unique potential risk factors evaluated

90

Risk factors with statistically significant association with CPAPGs

36

Original publication

Risk factors for a central-to-peripheral arterial blood pressure gradient in adults: a systematic review. Can J Anaesth. Published 13 January 2026. doi:10.1007/s12630-025-03058-3

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