Hemodynamics, fluids & transfusion
Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study
Authors' conclusion
Most bedside peripheral perfusion parameters were strongly interrelated, particularly PPI, SBFBT, and ΔT. In contrast, rSO₂ appeared poorly correlated and less predictive. CRT emerged as the most reliable marker of ICU mortality.
Study context
- Population
- Adult ICU patients with an expected stay ≥ 3 days
- Participants
- 55 patients
- Outcome
- Correlation between parameters
Main finding
As reported in the abstract
day 1
- Strong correlations between Peripheral Perfusion Index (PPI), Capillary Refill Time (CRT), SBFBT and ΔT
- rSO₂ showed no significant associations
Observational data: associations, not effects.
Secondary outcomes
| Outcome | CRT | MS |
|---|---|---|
| Prediction of ICU mortality | ||
| AUC | 0.75 | 0.72 |
| P | p = 0.007 | — not stated in the abstract |
— not stated in the abstract
Subgroup consistency of correlations (subgroup)
- Correlations strongest in circulatory shock, weaker in acute brain injury (ABI) and acute respiratory failure (ARF) subgroups
Prediction of ICU mortality
- CRT highest predictive value, followed by Mottling Score (MS), SBFBT and PPI; ΔT limited performance; rSO₂ weakest predictor
Original publication
Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study. Ann Intensive Care. Published 30 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →