Pain medicine

Risk factors for acute pain after transvaginal ultrasound-guided oocyte retrieval: a retrospective study (2023–2024)

Int J Obstet AnesthPublished Retrospective cohort study

Authors' conclusion

Younger age, pre-procedural pain, procedure duration, endometriosis and high basal anti-Mullerian hormone levels are risk factors

Study context

Population
Patients undergoing transvaginal ultrasound-guided oocyte retrieval, Montpellier University Hospital (France), June 30, 2023 to June 30, 2024
Participants
1,000 oocyte retrieval procedures
Outcome
Post-procedural pain (maximal NRS > 3 or rescue analgesia required)
Follow-up
Within 4 h
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Post-procedural pain

Incidence of post-procedural pain: 608 of 986 patients

61.66%

Independent risk factor (n=969): age, OR

0.96

P = 0.020

Independent risk factor (n=969): pre-procedural pain, OR

5.84

P < 0.001

Independent risk factor (n=969): procedure duration, OR

1.07

P < 0.001

Observational data: associations, not effects.

Secondary outcomes

Moderate to severe post-procedural pain (maximal NRS > 5 or morphine consumption) · within 4 h

Incidence: 227 of 982 patients
23.12%
Independent risk factor (n = 816): pre-procedural pain, OR
4.12, P < 0.001
Independent risk factor (n = 816): endometriosis, OR
2.23, P < 0.001
Independent risk factor (n = 816): anti-Mullerian hormone levels, OR
1.11, P = 0.009
Independent risk factor (n = 816): procedure duration, OR
1.05, P = 0.001

Original publication

Risk factors for acute pain after transvaginal ultrasound-guided oocyte retrieval: a retrospective study (2023–2024). Int J Obstet Anesth. Published 15 March 2026. doi:10.1016/j.ijoa.2026.104919

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