Neuroanaesthesia & neurocritical care

Risk factors for postoperative pneumonia following intracranial aneurysm surgery: a propensity score matching analysis

Perioper Med (Lond)Published Retrospective cohort study

Authors' conclusion

Six risk factors for POP after intracranial aneurysm surgery were identified in this study, some of which are modifiable.

Study context

Population
Adults (≥ 18 years) undergoing intracranial aneurysm surgery, January 2019 to July 2022668 matched analysed
Participants
1,115 adults
Exposure
Postoperative pneumonia (POP) vs no POP
  • POPn = 334
  • No POPn = 334reference
Outcome
Independent risk factors for POP
Methodological details1:1 propensity-score matched, single hospital
  • 1:1 propensity-score matched
  • Single hospital

Main finding

As reported in the abstract

Independent risk factors for POP (multivariate logistic regression)
  • Preoperative antimicrobial prophylaxis
  • Operative duration ≥ 4 h
  • Indwelling gastric tube
  • Intensive care unit (ICU) admission on the day of surgery
  • Postoperative use of analgesics or sedatives
  • White blood cell (WBC) count ≥ 10,000 cells/µL
  • After 1:1 propensity score matching

Observational data: associations, not effects.

Original publication

Risk factors for postoperative pneumonia following intracranial aneurysm surgery: a propensity score matching analysis. Perioper Med (Lond). Published 6 May 2026. doi:10.1186/s13741-026-00686-1

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