Risk of blood culture contamination during central venous catheter insertion in critically ill adults: a self-controlled study
Main finding · ContaminationResult — go to the resultOdds ratio 2.58 95% CI 1.21–5.51Authors' conclusion
Blood cultures obtained from the CVC hub during insertion were associated with an increased risk of contamination.
Study context
- Population
- Critically ill adults with blood cultures in an eight-bed adult ICU, June 2023–June 2025
- Participants
- 86 adults · 102 same-day matched pairs
- Exposure
- Central venous catheter (CVC)-insertion hub vs Comparator
- Outcome
- Blood culture contamination
Methodological detailssingle-centre, self-controlled, same-day within-patient paired analysis
- Single-centre
- Self-controlled
- Same-day within-patient paired analysis
Main finding
Contamination
Odds ratio
2.58
95% CI 1.21–5.51
CVC-insertion hub vs Comparator
OR 2.58 (95% CI 1.21–5.51)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Contamination, arterial-line comparator cultures and 7- and 14-day matching windows (sensitivity analyses)
- Finding consistent
Original publication
Risk of blood culture contamination during central venous catheter insertion in critically ill adults: a self-controlled study. J Crit Care. Published 13 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →