ICU sedation, delirium & recovery
Regional wall motion abnormalities (RWMAs) in critically ill patients with non‐obstructed coronary arteries
Main finding · Risk-adjusted 90-day mortalityResult — go to the resultOdds ratio 1.21 95% CI 0.56–2.64Authors' conclusion
RWMA can be seen to occur in critically ill patients in the absence of coronary artery obstruction.
Study context
- Population
- Critically ill intensive care unit (ICU) patients with RWMA on echocardiography who underwent angiography in conjunction with their ICU stay, 2012–2019
- Participants
- 53 vs 204
- Exposure
- RWMA with non-obstructed vs obstructed coronary arteries
- Non-obstructedn = 53
- Obstructedn = 204reference
- Outcome
- Risk-adjusted 90-day mortality
- Follow-up
- 90 days
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
Odds ratio
1.21
95% CI 0.56–2.64
P = 0.628
Non-obstructed vs Obstructed
OR 1.21 (95% CI 0.56–2.64); P = 0.628
Observational data: associations, not effects.
Further findings
| Outcome | Non-obstructed |
|---|---|
| Normalization of cardiac function on follow-up echocardiography (Non-obstructed) | |
| Follow-up echocardiography available | 38 |
Patient characteristics and ECG/biomarkers
- Non-obstructed more often female, younger, fewer cardiovascular risk factors
- Non-obstructed less commonly ST elevation, more frequently T-wave inversion or serious arrhythmias
- Troponin higher in Obstructed; NT-proBNP similar between groups
Cardiac magnetic resonance imaging (cMRI) diagnoses (Non-obstructed, n = 14)
- Tentative Takotsubo syndrome or myocardial stunning
- 7
- MI (preexisting in 3 cases)
- 4
- Acute myocarditis
- 1
- Post-myocarditis
- 1
- Dilated cardiomyopathy
- 1
Original publication
RWMAs in critically ill patients with non‐obstructed coronary arteries. Acta Anaesthesiol Scand. Published 23 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →