Respiratory failure & ventilation
Safety and efficacy of high frequency jet ventilation: A systematic and narrative review
Study context
- Population
- Adult and paediatric patients in operating room and ICU settings41 studies
- Comparison
- High-Frequency Jet Ventilation (HFJV) vs conventional ventilation strategies
- Outcome
- Safety and efficacy of HFJV
Methodological detailsPRISMA guidelines, Oxford Centre for Evidence-Based Medicine (OCEBM) levels of evidence, Cochrane risk-of-bias tools (RoB 2 and ROBINS-I), Common limitations: small sample sizes, methodological heterogeneity, risk of selection and publication bias
- PRISMA guidelines
- OCEBM levels of evidence
- Cochrane risk-of-bias tools (RoB 2 and ROBINS-I)
- Common limitations: small sample sizes, methodological heterogeneity, risk of selection and publication bias
Main finding
As reported in the abstract
- Most studies showed favourable physiological and procedural outcomes with HFJV intraoperatively, most notably in airway surgery, tissue ablation and AF ablation
- Neonatal intensive care: heterogeneous results, some studies improved gas exchange, others higher complication or mortality rates
- Volatile anaesthetic delivery universally unfeasible
- HFJV performance reduced in obese or COPD patients
Original publication
Safety and efficacy of high frequency jet ventilation: A systematic and narrative review. J Clin Anesth. Published 23 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →