Perioperative medicine & outcomes
Safety profile of a multimodal fail-safe model to minimize postoperative complications in oncologic colorectal resections—a cohort study
Authors' conclusion
The fail-safe model showed less postoperative complications even for low rectal anastomosis.
Study context
- Population
- Patients with colorectal cancer undergoing surgical resection with anastomosis924 operated in total
- Participants
- 696 patients
- Exposure
- Multimodal fail-safe model vs control
- Fail-safen = 510
- Controln = 186reference
- Outcome
- Major complications (Dindo-Clavien grade IIIb-V)
Methodological detailshistorical control comparison, Operations: 427 (61.4%) laparoscopic, 230 (33.0%) open, 39 (5.6%) converted laparoscopic
- Historical control comparison
- Operations: 427 (61.4%) laparoscopic, 230 (33.0%) open, 39 (5.6%) converted laparoscopic
Main finding
As reported in the abstract
P < 0.0001
Observational data: associations, not effects.
Safety
Anastomotic leakage
P < 0.0001
Original publication
Safety profile of a multimodal fail-safe model to minimize postoperative complications in oncologic colorectal resections—a cohort study. Perioper Med (Lond). Published 11 March 2023. doi:10.
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