Pain medicine

Sarcopenia is associated with an increase in long-term use of analgesics after elective surgery under general anesthesia

Reg Anesth Pain MedPublished Population-based propensity-score matched cohort study

Authors' conclusion

Sarcopenia is associated with higher rates of long-term non-opioid analgesic and opioid use after elective surgery under general anesthesia.

Study context

Population
Patients undergoing elective surgery under GA, Taiwan, 1 October 2016 to 31 December 2019
Participants
2,860 patients
Exposure
Presurgical sarcopenia vs no sarcopenia
Outcome
Combined rate of long-term use of all non-opioid analgesics or opioids
Follow-up
3 and 6 months after elective surgery
Methodological detailsTaiwan National Health Insurance Research Database
  • Taiwan National Health Insurance Research Database

Main finding

As reported in the abstract

Long-term non-opioid analgesic and opioid use · 3 and 6 months
Sarcopenia vs Non-sarcopeniaAdjusted odds ratio (95% CI)
Non-opioid analgesic use, 3 months
1.17(1.05–2.23)
Non-opioid analgesic use, 6 months
1.26(1.04–1.45)
Opioid use, 3 months
1.17(1.07–2.21)
Opioid use, 6 months
1.23(1.10–3.64)

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Sarcopenia is associated with an increase in long-term use of analgesics after elective surgery under general anesthesia. Reg Anesth Pain Med. Published 11 January 2023. doi:10.1136/rapm-2022-104144

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