Second-Generation Supraglottic Airway Devices Versus Endotracheal Intubation in Adults Undergoing Abdominopelvic Surgery: A Systematic Review and Meta-Analysis
Pooled result · Major perioperative airway complicationsResult — go to the resultRelative risk 0.41 95% CI 0.23–0.71Authors' conclusion
Second-generation SGAs reduce the risk of major airway complications compared with ETTs in adults undergoing abdominopelvic procedures under general anesthesia, with no reported clinically relevant differences in the risk of regurgitation or pulmonary aspiration.
Study context
- Population
- Adults undergoing abdominopelvic surgery under GA
- Participants
- 5,110 adults · 51 studies
- Comparison
- Second-generation supraglottic airway (SGAs) vs endotracheal tubes (ETTs)
- Outcome
- Major perioperative airway complications
Methodological detailspairwise meta-analysis, grading of recommendations, assessment, development, and evaluation (GRADE) certainty assessment
- Pairwise meta-analysis
- GRADE certainty assessment
Pooled result
As reported in the abstract
Relative risk
0.41
95% CI 0.23–0.71
P = 0.007
SGA vs ETT
RR 0.41 (95% CI 0.23–0.71); P = 0.007
Further pooled results
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Postoperative sore throatModerate certainty | 0.52 (0.38–0.70) | P < 0.001 | |
| HoarsenessLow certainty | 0.32 (0.231–0.48) | P < 0.001 | |
| Coughing at emergenceLow certainty | 0.17 (0.08–0.36) | P < 0.001 | |
| PONVVery low certainty | 0.64 (0.42–0.98) | P = 0.042 | |
| 0.050.21520Relative risk (log scale) |
Other remaining outcomes
- No other clinically relevant differences
Safety
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Inadequate ventilationVery low certainty | 3.36 (1.43–7.89) | P = 0.011 | |
| 0.10.31310Relative risk (log scale) |
Regurgitation or pulmonary aspiration
- No clear clinically relevant difference
- Low certainty
Original publication
Second-Generation Supraglottic Airway Devices Versus Endotracheal Intubation in Adults Undergoing Abdominopelvic Surgery: A Systematic Review and Meta-Analysis. Anesth Analg. Published 10 January 2025. doi:10.
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