ICU sedation, delirium & recovery
Sedation practices and associated clinical outcomes among adult intensive care unit (ICU) patients managed by advanced practice providers versus resident physicians
Authors' conclusion
Patients admitted to an APP-staffed ICU were more likely to have sedation management reflective of best practice, and this practice was associated with shorter time to extubation and lower mortality.
Study context
- Population
- Adults in two medical ICUs requiring invasive ventilation for at least 48 h
- Participants
- 337 adults
- Exposure
- APP-staffed vs resident-staffed ICU
- Outcome
- Association of staffing model with sedative exposure
- Follow-up
- First week of mechanical ventilation
Methodological detailstwo medical ICUs, quaternary teaching hospital
- Two medical ICUs
- Quaternary teaching hospital
Main finding
As reported in the abstract
Sedative exposure · day of intubation
APP ICU vs Resident ICUAdjusted odds ratio (95 % CI)P value
Benzodiazepine exposure
0.63(0.40–0.99)
P = 0.04Propofol exposure
1.73(1.07–2.79)
P = 0.03Observational data: associations, not effects.
Further findings
Time to extubation, propofol on first day vs not
| aHR (95 % CI) | P value | ||
|---|---|---|---|
| Propofol on first day | 1.45 (1.07–1.98) | P = 0.02 | |
| 0.512Adjusted hazard ratio (log scale) |
In-hospital mortality, propofol on first day vs not
| aOR (95 % CI) | P value | ||
|---|---|---|---|
| Propofol on first day | 0.55 (0.33–0.93) | P = 0.02 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Continuous sedation on day of intubation (all patients)
- Received continuous sedation
- 96 %
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Sedation practices and associated clinical outcomes among adult ICU patients managed by advanced practice providers versus resident physicians. J Crit Care. Published 11 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →