Pain medicine

Sex Differences in Chronic Postsurgical Pain after Open Thoracotomy

J Cardiothorac Vasc AnesthPublished Observational cohort study

Authors' conclusion

These findings show that the incidence of physician-diagnosed chronic postsurgical pain is higher in women than in men after surgeries involving thoracotomy.

Study context

Population
Patients scheduled for open thoracotomy, 10 university-affiliated hospitals
Participants
96 vs 137
Exposure
Women vs men
  • Womenn = 96
  • Menn = 137reference
Outcome
Incidence of chronic postsurgical pain (diagnosed by physical examination)
Follow-up
4 months
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Chronic postsurgical pain incidence

P = 0.023

Observational data: associations, not effects.

Secondary outcomes

OutcomeP value
Baseline psychological measuresWomen vs Men · perception of mental stateP = 0.01
Baseline psychological measuresWomen vs Men · depressionP = 0.006
Baseline psychological measuresWomen vs Men · catastrophizingP < 0.001
Preoperative painWomen vs Men · operative areaP = 0.011
Preoperative painWomen vs Men · other areasP = 0.030

Baseline psychological measures

Women had significantly worse scores on psychological measures

Preoperative pain

Women reported more preoperative pain

Original publication

Sex Differences in Chronic Postsurgical Pain after Open Thoracotomy. J Cardiothorac Vasc Anesth. Published 4 September 2024. doi:10.1053/j.jvca.2024.08.039

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