Cardiothoracic & vascular anesthesia

Pain management after open thoracotomy 2025: procedure‐specific postoperative pain management ( PROSPECT ) recommendations

AnaesthesiaPublished Procedure-specific guideline

Methodological detailssystematic review-based recommendations, systematic review of RCTs, systematic reviews and meta-analyses, modified Delphi approach, Cochrane Risk of bias tool 2
  • Systematic review-based recommendations
  • Systematic review of RCTs, systematic reviews and meta-analyses
  • Modified Delphi approach
  • Cochrane Risk of bias tool 2

Recommendations

As issued by the authors

  1. Thoracic epidural analgesia or paravertebral blockade as first-line analgesic intervention

  2. ESP, rhomboid intercostal or intercostal nerve blockade could be used as second-line regional analgesia

  3. Basic analgesia: paracetamol and NSAIDs or cyclo-oxygenase-2 selective inhibitors

  4. low level of supportive evidence

    Acupuncture or cryoanalgesia when regional analgesia cannot be performed

  5. Surgical technique, postoperative physiotherapy and patient education to be based on outcomes other than pain control

  6. Other regional blocks limited to patients who cannot receive thoracic epidural analgesia or paravertebral blockade

Original publication

Pain management after open thoracotomy 2025: procedure‐specific postoperative pain management ( PROSPECT ) recommendations. Anaesthesia. Published 12 January 2026. doi:10.1111/anae.70123

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