Cardiac arrest & resuscitation
Sex differences in extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: nationwide multicenter retrospective study in Japan
Primary result · Favorable neurological outcome (CPC 1 or 2) at hospital dischargeResult — go to the resultAdjusted odds ratio 1.60 95% CI 1.05–2.43Authors' conclusion
The female sex is significantly associated with favorable neurological outcomes at hospital discharge in patients who received ECPR for OHCA.
Study context
- Population
- Adults without external causes who underwent extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA), Japan, 2013–2018
- Participants
- 1,819 adults
- Comparison
- Women vs men undergoing ECPR for OHCA
- Womenn = 296
- Menn = 1,523reference
- Primary endpoint
- Favorable neurological outcome (Cerebral Performance Status 1 or 2)
- Follow-up
- Hospital discharge
Methodological detailsretrospective multicentre study, nationwide, multilevel logistic regression
- Retrospective multicentre study
- Nationwide
- Multilevel logistic regression
Primary result
As reported in the abstract
Favorable neurological outcome (CPC 1 or 2) at hospital discharge
Adjusted odds ratio
1.60
95% CI 1.05–2.43
P = 0.03
By group
Women vs men undergoing ECPR for OHCA
aOR 1.60 (95% CI 1.05–2.43); P = 0.03
- Unadjusted difference between males and females
- P = 0.10
Further findings
Initial non-shockable rhythm
Non-shockable rhythm at hospital arrival
Non-shockable rhythm at ECMO initiation
Age, witnessed arrest, bystander CPR
- Similar between groups
Original publication
Sex differences in extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: nationwide multicenter retrospective study in Japan. Crit Care. Published 31 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →