Perioperative medicine & outcomes

Sex differences in myocardial injury after non-cardiac surgery and postoperative mortality

Perioper Med (Lond)Published Retrospective cohort study

Main finding · Incidence of MINSResult — go to the resultOdds ratio 0.76 95% CI 0.71–0.81

Authors' conclusion

The incidence of MINS was lower in women than in men. In patients with MINS, female sex may be associated with a survival benefit.

Study context

Population
Consecutive patients with cardiac troponin measured within 30 days after non-cardiac surgery, January 2010–June 2019, single tertiary referral hospital
Participants
33,311 patients
Exposure
Women vs men
  • Womenn = 14,765
  • Menn = 18,546reference
Outcome
Incidence of MINS
Methodological detailssingle-centre, multivariable analysis, propensity-score matched
  • Single-centre
  • Multivariable analysis
  • Propensity-score matched

Main finding

As reported in the abstract

Odds ratio

0.76

95% CI 0.71–0.81

P < 0.001

By group

Women vs Men
OR 0.76 (95% CI 0.71–0.81); P < 0.001

Observational data: associations, not effects.

Further findings

30-day mortality in patients with MINS

30-day mortality did not differ according to sex
  • Propensity-score-matched analysis

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Sex differences in myocardial injury after non-cardiac surgery and postoperative mortality. Perioper Med (Lond). Published 16 March 2023. doi:10.1186/s13741-023-00294-3

Composed by AI from the published abstract and checked against it. How Briefs are made →

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