Cardiothoracic & vascular anesthesia
Sex-Based Differences in Ruptured Abdominal Aortic Aneurysm Management and Outcomes: An Update
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 1.27 CI 1.12–1.44Authors' conclusion
Significant sex-based disparities were found in AAA repair outcomes. Men had higher comorbidity burdens while women presented at an older age with an increased time from symptom onset to repair.
Study context
- Population
- Patients undergoing open or endovascular repair for ruptured abdominal aortic aneurysm (AAA), January 2003 to December 2022
- Participants
- 7,548 patients
- Exposure
- Women vs men
- Womenn = 1,719
- Menn = 5,829reference
- Outcome
- In-hospital mortality
Methodological detailsmulti-institutional, Vascular Quality Initiative national database
- Multi-institutional
- Vascular Quality Initiative national database
Main finding
As reported in the abstract
Odds ratio
1.27
CI 1.12–1.44
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | OR (CI) | P value | |
|---|---|---|---|
| Cardiovascular complicationsWorse in men | 0.82 (0.72–0.94) | P = 0.005 | |
| Pulmonary complicationsWorse in men | 0.86 (0.73–1.00) | P = 0.025 | |
| 0.512Odds ratio (log scale) |
Age at presentation
P < 0.001
Time from symptom onset to repair
P = 0.002
Comorbidities: coronary artery disease
P < 0.001
Prior percutaneous coronary intervention
P = 0.004
Previous aneurysm repair
P = 0.005
Hypertension
P = 0.008
Mortality trend 2003 to 2022
- Women: mortality 57.1% to 31.6%
- Men: mortality 38.5% to 19.6%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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