Cardiothoracic & vascular anesthesia
Cardiopulmonary exercise testing, computed tomography-derived body composition, systemic inflammation and survival after elective abdominal aortic aneurysm repair: A retrospective cohort study
Main finding · Survival by CT-SS and long-term mortalityResult — go to the resultHR for long-term mortality 1.83 95% CI 1.16–2.89Authors' conclusion
CPEX test results were not consistently associated with body composition and did not have significant prognostic value in patients undergoing elective treatment for AAA.
Study context
- Population
- Patients undergoing elective endovascular aneurysm repair (EVAR) or open surgical repair for abdominal aortic aneurysm (AAA), single secondary-care centre, 31 March 2015 to 25 June 2020130 EVAR, 46 open surgical repair (OSR)
- Participants
- 176 patients
- Exposure
- Computed tomography (CT) sarcopenia score 0 vs 1 vs 2; CPEX results
- Outcome
- Association of CT-BC (CT-SS), CPEX and systemic inflammation (modified Glasgow Prognostic score (mGPS)) with survival
Methodological detailssingle-centre, Median (IQR) follow-up 60.5 [27] months; all completed ≥2 years follow-up
- Single-centre
- Median (IQR) follow-up 60.5 [27] months; all completed ≥2 years follow-up
Main finding
Survival by CT-SS and long-term mortality
HR for long-term mortality
1.83
95% CI 1.16–2.89
P < 0.01
By group
Elevated CT-SS
HR for long-term mortality 1.83 (95% CI 1.16–2.89); P < 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
- CT-SS not associated with CPEX results
- P > 0.05
Original publication
Cardiopulmonary exercise testing, computed tomography-derived body composition, systemic inflammation and survival after elective abdominal aortic aneurysm repair: A retrospective cohort study. Eur J Anaesthesiol. Published 16 May 2024. doi:10.
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