Sex-related mortality differences in septic shock: A propensity score–matched study
Main findingResult — go to the resultRelative risk 0.92 95% CI 0.89–0.95Authors' conclusion
Mortality in young women with septic shock was lower than in young men suggesting sex-related differences
Study context
- Population
- Young adults (18–55 years) developing septic shock, January 2011 to January 202086,748 matched
- Participants
- 100,894 adults
- Exposure
- Women vs men
- Womenn = 43,374
- Menn = 43,374reference
- Outcome
- All-cause mortality
- Follow-up
- 28 days
Methodological detailspropensity score-matched, TriNetX network
- Propensity score-matched
- TriNetX network
Main finding
As reported in the abstract
Relative risk
0.92
95% CI 0.89–0.95
P < 0.001
Events by group
Women vs Men
RR 0.92 (95% CI 0.89–0.95); P < 0.001
Observational data: associations, not effects.
Secondary outcomes
90-day and 180-day mortality
- Similar results to 28-day mortality
Original publication
Sex-related mortality differences in septic shock: A propensity score–matched study. J Crit Care. Published 14 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →