Perioperative medicine & outcomes

Sex-Specific Associations Between Preoperative Hemoglobin and Outcomes After Major Noncardiac Surgery: A Retrospective Cohort Study

Anesth AnalgPublished Retrospective cohort study

Authors' conclusion

Low preoperative hemoglobin was associated with a higher risk of complications or mortality after elective noncardiac surgery in both men and women. No differences in the strength of associations between sexes were found.

Study context

Population
Adults undergoing elective major noncardiac surgery in a large academic hospital
Participants
22,550 adults
Exposure
Preoperative hemoglobin, women vs men
  • Womenn = 9,268
  • Menn = 13,282
Outcome
Composite of:
  • Postoperative mortality or cardiovascular
  • Renal
  • Pulmonary
  • Infectious complications
Follow-up
During hospitalization
Methodological detailssingle-centre, multivariable-adjusted, sex-stratified
  • Single-centre
  • Multivariable-adjusted
  • Sex-stratified

Main finding

As reported in the abstract

Primary composite outcome
Multivariable-adjusted
Odds ratio per 1 g/dL increase in hemoglobin (95% CI)P value
Women
0.93(0.87–0.98)
P = 0.013
Men
0.94(0.90–0.97)
P < 0.001

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Sex-Specific Associations Between Preoperative Hemoglobin and Outcomes After Major Noncardiac Surgery: A Retrospective Cohort Study. Anesth Analg. Published 20 October 2023. doi:10.1213/ane.0000000000006661

Composed by AI from the published abstract and checked against it. How Briefs are made →

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