Hemodynamics, fluids & transfusion

Should the Vasoactive Inotropic Score be a Determinant for Early Initiation of VA ECMO in Postcardiotomy Cardiogenic Shock?

J Cardiothorac Vasc AnesthPublished Retrospective multicentre observational study

Authors' conclusion

When matching integrated the pre-ECMO VIS and the type of catecholamines, VA ECMO remained associated with high mortality and morbidity

Study context

Population
Patients with postcardiotomy cardiogenic shock (PCS) in the operating roomscreened
Participants
2,742 patients
Exposure
Early VA ECMO vs matched control
  • VA ECMOn = 75
Outcome
Mortality
Methodological detailspropensity-weight matching, 4 university-affiliated ICUs, 424 (16%) treated with inotropic drugs
  • Propensity-weight matching
  • 4 university-affiliated ICUs
  • 424 (16%) treated with inotropic drugs

Main finding

As reported in the abstract

P < 0.001

Observational data: associations, not effects.

Further findings

Pre-ECMO catecholamine support

Higher vasopressor and inotrope use, with higher vasoactive-inotropic score (VIS), in VA ECMO patients
  • Before matching

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Should the Vasoactive Inotropic Score be a Determinant for Early Initiation of VA ECMO in Postcardiotomy Cardiogenic Shock? J Cardiothorac Vasc Anesth. Published 1 December 2023. doi:10.1053/j.jvca.2023.11.040

Composed by AI from the published abstract and checked against it. How Briefs are made →

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