Hemodynamics, fluids & transfusion
Should the Vasoactive Inotropic Score be a Determinant for Early Initiation of VA ECMO in Postcardiotomy Cardiogenic Shock?
Authors' conclusion
When matching integrated the pre-ECMO VIS and the type of catecholamines, VA ECMO remained associated with high mortality and morbidity
Study context
- Population
- Patients with postcardiotomy cardiogenic shock (PCS) in the operating roomscreened
- Participants
- 2,742 patients
- Exposure
- Early VA ECMO vs matched control
- VA ECMOn = 75
- Outcome
- Mortality
Methodological detailspropensity-weight matching, 4 university-affiliated ICUs, 424 (16%) treated with inotropic drugs
- Propensity-weight matching
- 4 university-affiliated ICUs
- 424 (16%) treated with inotropic drugs
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Pre-ECMO catecholamine support
- Higher vasopressor and inotrope use, with higher vasoactive-inotropic score (VIS), in VA ECMO patients
- Before matching
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Should the Vasoactive Inotropic Score be a Determinant for Early Initiation of VA ECMO in Postcardiotomy Cardiogenic Shock? J Cardiothorac Vasc Anesth. Published 1 December 2023. doi:10. 1053/ j. jvca. 2023. 11. 040
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