Respiratory failure & ventilation

Similar Weaning Success Rate with High-Intensity and Sham Inspiratory Muscle Training: A Randomized Controlled Trial (IMweanT)

Am J Respir Crit Care MedPublished Randomised controlled trial

Authors' conclusion

Both high-intensity IMT and sham low-intensity IMT, with high adherence to the protocol, resulted in similar weaning success rates and pronounced improvements in maximal inspiratory muscle strength.

Study context

Population
Patients with weaning difficulties
Comparison
High-intensity inspiratory muscle training (IMT) vs sham low-intensity IMT
Methodological detailssham-controlled
  • Sham-controlled

Primary result

As reported in the abstract

Weaning success

P = 0.43

Further findings

Training adherence (completed/planned sessions)

P = 0.25

Weaning duration

P = 0.33

OutcomeHi-IMTLo-IMTP value
Change in PImax+15 (95% CI 9–20) cm H2O+14 (95% CI 9–19) cm H2OP = 0.72
Change in FVCFVC improved more in Hi-IMT+0.33 (95% CI 0.22–0.43) L+0.16 (95% CI 0.07–0.25) LP = 0.04

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Similar Weaning Success Rate with High-Intensity and Sham Inspiratory Muscle Training: A Randomized Controlled Trial (IMweanT). Am J Respir Crit Care Med. Published 1 March 2025. doi:10.1164/rccm.202405-1042oc

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