Single-bolus injection of local anesthetic, with or without continuous infusion, for interscalene brachial plexus block in the setting of multimodal analgesia: a randomized controlled unblinded trial
Authors' conclusion
A continuous infusion of local anesthetic for an interscalene brachial plexus block does not provide superior analgesia after major shoulder surgery when compared with a single injection in the setting of multimodal analgesia, inclusive of intravenous dexamethasone, magnesium, acetaminophen and ketorolac.
Study context
- Population
- Patients undergoing shoulder arthroplasty or arthroscopic rotator cuff repair, with multimodal analgesia (IV dexamethasone, magnesium, acetaminophen, ketorolac) and IV morphine PCA
- Participants
- 60 patients
- Comparison
- Continuous infusion vs Single injection
- Primary endpoint
- Cumulative IV morphine consumption
- Follow-up
- 24 hours postoperatively
Methodological detailsunblinded
- Unblinded
Primary result
As reported in the abstract
P = 0.74
Secondary outcomes
Pain scores at rest and on movement, and functional outcomes, over 48 hours
- No significant between-group differences for any secondary outcome
Original publication
Single-bolus injection of local anesthetic, with or without continuous infusion, for interscalene brachial plexus block in the setting of multimodal analgesia: a randomized controlled unblinded trial. Reg Anesth Pain Med. Published 4 August 2023. doi:10.
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