Cardiac arrest & resuscitation
Sleep apnea, the risk of out-of-hospital cardiac arrest, and potential benefits of continuous positive airway pressure therapy: A nationwide study
Authors' conclusion
SA not treated with CPAP was associated with OHCA, while no increased risk of OHCA was found for SA patients treated with CPAP.
Study context
- Population
- General population, nationwide databases: Out-of-hospital cardiac arrest (OHCA) cases of presumed cardiac causes and matched non-OHCA controls46,578 cases
- Comparison
- Sleep apnea (SA) with or without continuous positive airway pressure (CPAP) vs no SA
- Outcome
- OHCA
Methodological detailsnationwide, age/sex/OHCA-date matched, conditional logistic regression, Mean age 71 years, 68.8% men
- Nationwide
- age/sex/OHCA-date matched
- Conditional logistic regression
- Mean age 71 years, 68.8% men
Main finding
As reported in the abstract
Each group vs no SAOdds ratio (95% CI)
SA without CPAP
1.20(1.06–1.36)
SA with CPAP
1.04(0.93–1.36)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| OHCA, patients with neither ischemic heart disease nor HF (subgroup)SA without CPAP vs No SA | 1.24 (1.04–1.47) | |
| OHCA, patients with neither ischemic heart disease nor HF (subgroup)SA with CPAP vs No SA | 1.08 (0.93–1.25) | |
| OHCA, patients without CVD (subgroup)SA without CPAP vs No SA | 1.33 (1.07–1.65) | |
| OHCA, patients without CVD (subgroup)SA with CPAP vs No SA | 1.14 (0.94–1.39) | |
| 0.512Odds ratio (log scale) |
Original publication
Sleep apnea, the risk of out-of-hospital cardiac arrest, and potential benefits of continuous positive airway pressure therapy: A nationwide study. Resuscitation. Published 11 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →