Hemodynamics, fluids & transfusion
Sodium and chloride disturbances in critically ill adult patients: A protocol for a sub‐study of the FLUID‐intensive care unit (ICU) cohort study
Study context
- Population
- Adults admitted to the ICUplanned minimum 1000
- Primary endpoint
- Proportion of patients with hypernatremia, hyponatremia, hyperchloremia, and hypochloremia
Methodological details14-day inception cohort, multicentre (more than 50 ICUs), Daily follow-up from ICU admission to discharge or death (maximum 28 days); follow-up at Day 90, Planned assessments: days alive without life support at Day 90; risk factors (SMS-ICU score, ICU type, diuretics, fluid accumulation); days alive and out of hospital and mortality at Day 90 reported descriptively
- 14-day inception cohort
- Multicentre (more than 50 ICUs)
- Daily follow-up from ICU admission to discharge or death (maximum 28 days); follow-up at Day 90
- Planned assessments: days alive without life support at Day 90; risk factors (SMS-ICU score, ICU type, diuretics, fluid accumulation); days alive and out of hospital and mortality at Day 90 reported descriptively
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Sodium and chloride disturbances in critically ill adult patients: A protocol for a sub‐study of the FLUID‐ICU cohort study. Acta Anaesthesiol Scand. Published 24 March 2025. doi:10.
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