Strategies to Limit Benzodiazepine Use in Anesthesia for Older Adults: A Randomized Clinical Trial
Authors' conclusion
This randomized clinical trial found that clinician peer comparison, patient informational mail, or a combination of both interventions did not reduce benzodiazepine administration to older patients compared with usual care; patient satisfaction remained high throughout the study.
Study context
- Population
- Adults aged ≥65 years undergoing elective surgical or endoscopic procedures with GA at 415 hospitals, surgery centers and physician offices in 8 US statesenrolled
- Participants
- 509,269 adults
- Comparison
- Clinician peer comparison, patient informational mail, or both vs usual care
- Clinician peer comparisonn = 81,363
- Patient informational mailn = 98,520
- Both interventionsn = 169,712
- Usual caren = 159,674reference
- Primary endpoint
- Rate of benzodiazepine administration during anesthesia care and patient satisfaction with anesthesia care (Anesthesia Patient Satisfaction Questionnaire, version 2)
Methodological details2 × 2 factorial, stepped-wedge, cluster randomized, quality improvement initiative, intention-to-treat
- 2 × 2 factorial
- Stepped-wedge
- Cluster randomized
- Quality improvement initiative
- Intention-to-treat
Primary result
As reported in the abstract
Benzodiazepine administration during anesthesia care
Each group vs usual careOdds ratio (95% CI)P value
Clinician peer comparison
1.02(0.98–1.07)
P = 0.35Patient informational mail
1.01(0.96–1.05)
P = 0.81Both interventions
1.11(1.05–1.16)
P < 0.001Original publication
Strategies to Limit Benzodiazepine Use in Anesthesia for Older Adults: A Randomized Clinical Trial. JAMA Netw Open. Published 1 October 2024. doi:10.
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