Organ support & nutrition

Sublingual microcirculation: comparison between the 415 nm blue light and 520 nm green light of sidestream dark field videomicroscopes

J Clin Monit ComputPublished Diagnostic method comparison study

Authors' conclusion

Blue light provides a higher microcirculatory vessel density and image quality than the existing SDF probe using green light.

Study context

Population
Healthy volunteers (sublingual microcirculation) and ICU patients' sublingual microcirculation films
Participants
21 healthy volunteers
Comparison
415 nm blue light vs 520 nm green light sidestream dark field (SDF) probes
Outcome
Sublingual microcirculatory image quality and related microcirculatory parameters
Methodological detailsprospective healthy-volunteer cohort, retrospective scoring of ICU patient films, paired comparison
  • Prospective healthy-volunteer cohort
  • Retrospective scoring of ICU patient films
  • Paired comparison

Performance

As reported in the abstract

Vessel density in healthy volunteers

Increase in perfused vessel density

4.6 ± 4.7 mm/mm²

P < 0.0001

Blue light

Increase in total vessel density

5.1 ± 4.6 mm/mm²

P < 0.0001

Blue light

Further findings

OutcomeBlue lightGreen lightP value
Unacceptable films (image quality), ICU patients, 200 filmsRetrospectively scored10/10039/100P < 0.0001

Original publication

Sublingual microcirculation: comparison between the 415 nm blue light and 520 nm green light of sidestream dark field videomicroscopes. J Clin Monit Comput. Published 15 July 2022. doi:10.1007/s10877-022-00891-5

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