Subpectoral plexus block to enhance surgical anesthesia produced by a multilevel thoracic paravertebral block for primary breast cancer surgery: a prospective randomized double-blind study
Authors' conclusion
A SPPB enhances the surgical anesthesia produced by a 6m-TPVB for primary breast cancer surgery.
Study context
- Population
- Patients undergoing primary breast cancer surgery under a 6m-TPVB (T1-T6) with conscious sedation
- Participants
- 60 patients
- Comparison
- Gp-A vs Gp-B
- Gp-An = 30
- Gp-Bn = 30reference
- Primary endpoint
- Ketamine rescue analgesia for pain during surgery
Methodological detailsprospective, double-blind, sham-controlled
- Prospective
- Double-blind
- Sham-controlled
Primary result
As reported in the abstract
Patients requiring ketamine rescue analgesia
P = 0.002
Further findings
Ketamine requirement
P < 0.001
Mean
| Outcome | Gp-A | Gp-B | P value |
|---|---|---|---|
| Surgeon satisfaction with surgical conditions (NRS 0-100) | 77.29 (SD 10.63) | 65.83 (SD 21.38) | P = 0.02 |
Midazolam and dexmedetomidine dose, duration of surgery, patient satisfaction
- Comparable in the two groups
Original publication
Subpectoral plexus block to enhance surgical anesthesia produced by a multilevel thoracic paravertebral block for primary breast cancer surgery: a prospective randomized double-blind study. Reg Anesth Pain Med. Published 3 February 2025. doi:10.
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