Substance-dependent EEG during recovery from anesthesia and optimization of monitoring
Authors' conclusion
Systematic differences of EEG-based indices depend on the drugs and devices used.
Study context
- Population
- Patients under GA during anesthesia emergence
- Participants
- 45 participants
- Exposure
- Sevoflurane vs Isoflurane vs Propofol
- Sevofluranen = Fifteen
- Isofluranen = Fifteen
- Propofoln = Fifteenreference
- Outcome
- Dynamics of different EEG indices during anesthesia emergence
Methodological detailsEEG replay analysis, EEG replayed to multiple monitors
- EEG replay analysis
- EEG replayed to multiple monitors
Main finding
As reported in the abstract
- Volatile anesthetics induced significantly higher EEG frequencies, causing higher indices over most of emergence vs propofol
- AUC > 0.7
- Median duration of "awake" indices (> 80) before return of responsiveness significantly longer for volatile anesthetics
- p < 0.001
- Indices correlated well under volatile anesthesia, SE weakest
- rs > 0.6
- Correlation lower for propofol
- rs < 0.6
Observational data: associations, not effects.
Original publication
Substance-dependent EEG during recovery from anesthesia and optimization of monitoring. J Clin Monit Comput. Published 18 December 2023. doi:10.
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