Superficial Cervical Plexus Block and Quality of Recovery after Thyroidectomy: A Randomized Clinical Trial
Primary result · QoR-40 scoreResult — go to the resultAdjusted mean difference 0.91 95% CI −3.57 to 5.40Authors' conclusion
Bilateral superficial cervical plexus blocks did not improve quality of recovery after thyroidectomy when added to a multimodal analgesic regimen including dexamethasone, acetaminophen, nonsteroidal anti-inflammatory drugs, and incisional local anesthetic but were associated with lower total PACU opioid consumption.
Study context
- Population
- Adults undergoing thyroidectomy with GA, all receiving multimodal analgesia (dexamethasone, acetaminophen, NSAIDs, incisional local anaesthetic)randomised
- Participants
- 160 adults
- Comparison
- Bupivacaine vs Saline
- Bupivacainen = 78
- Salinen = 82reference
- Primary endpoint
- Quality of recovery (QoR-40 survey)
- Follow-up
- POD 1
Methodological detailssingle-centre, prospective, double-blind, placebo-controlled
- Single-centre
- Prospective
- Double-blind
- Placebo-controlled
Primary result
QoR-40 score
Adjusted mean difference
0.91
95% CI −3.57 to 5.40
P = 0.688
By group
Bupivacaine
174
mean · 95% CI 170–178
Saline
173
mean · 95% CI 169–177
Bupivacaine vs Saline
adjusted mean difference 0.91 (95% CI −3.57 to 5.40); P = 0.688
As reported in the abstract
Secondary outcomes
| Outcome | Bupivacaine | Saline | Difference (95% CI) | P value | |
|---|---|---|---|---|---|
| Rescue antiemetics | 3.8% | 16% | −12% (−22% to −1.8%) | P = 0.011 | |
| −30−20−10010Difference (linear scale) |
Median
| Outcome | Bupivacaine | Saline | Hodges-Lehmann location shift (morphine milligram equivalents) (95% CI) | P value |
|---|---|---|---|---|
| Total opioid administered in PACU | 0 (IQR 0–8) | 2 (IQR 0–20) | 0 (−4 to 0) | P = 0.017 |
Need for opioids in postanesthesia care unit (PACU) or on POD 1, nausea, vomiting, PACU LOS
- No significant between-group differences
Original publication
Superficial Cervical Plexus Block and Quality of Recovery after Thyroidectomy: A Randomized Clinical Trial. Anesthesiology. Published 10 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →