Surgical opioid-avoidance protocol: a postoperative pharmacological multimodal analgesic intervention in diverse patient populations
Authors' conclusion
The SOAP was as effective as the non-SOAP group in postoperative pain scores across a diverse patient population and associated with lower postoperative opioid consumption and discharge prescription opioids.
Study context
- Population
- Diverse, opioid-naive patients undergoing inpatient surgery across multiple surgical servicesgroups by surgery date
- Participants
- 449 vs 382
- Exposure
- Surgical opioid-avoidance protocol vs pre-existing non-SOAP protocol
- Surgical opioid-avoidance protocol (SOAP)n = 449
- non-SOAPn = 382reference
- Outcome
- Postoperative pain scores
Methodological detailsnon-inferiority, multiple surgical services
- Non-inferiority
- Multiple surgical services
Main finding
As reported in the abstract
- Postoperative pain scores with SOAP non-inferior to non-SOAP
- SOAP vs non-SOAP: 95% CI −0.58 to 0.10
- Non-inferiority margin=−1
Observational data: associations, not effects.
Further findings
Postoperative opioid consumption
P < 0.01
Discharge prescription opioids
P < 0.01
Original publication
Surgical opioid-avoidance protocol: a postoperative pharmacological multimodal analgesic intervention in diverse patient populations. Reg Anesth Pain Med. Published 6 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →