Cardiac arrest & resuscitation

Survival following cardiac arrest is associated with lower spontaneous echo contrast of cardiac chamber blood. A retrospective analysis of echocardiograms from a large cardiac arrest study

ResuscitationPublished Retrospective cohort study

Authors' conclusion

SEC is common following cardiac arrest. Patients with higher digital greyscale measurement of right ventricular cardiac chamber blood were less likely to demonstrate ROSC or survival to hospital admission.

Study context

Population
Patients presenting to the ED after OHCA with digitally recorded echocardiograms
Participants
717 patients
Exposure
Spontaneous echo contrast (SEC) vs no SEC on echocardiography after OHCA
Outcome
Survival to hospital discharge
Methodological detailsmulticentre, blinded image review
  • Multicentre
  • Blinded image review

Main finding

As reported in the abstract

  • Less common with SEC, but the difference did not reach statistical significance

Observational data: associations, not effects.

Secondary outcomes

Survival to hospital admission

P = 0.0065

ROSC and survival to hospital admission, by higher right ventricular (RV) greyscale

OR (CI)P value
Higher RV greyscaleROSC0.21 (0.05–0.85)P = 0.0291
Higher RV greyscaleSurvival to hospital admission0.14 (0.02–0.14)P = 0.0230
Prevalence of SEC
32.2 %
  • Median RV greyscale by outcome: Survived to discharge median 29
  • Median RV greyscale by outcome: Survived to admission median 33
  • Median RV greyscale by outcome: ROSC median 37
  • Median RV greyscale by outcome: Died in ED without ROSC median 45

ROSC and survival to hospital admission, by higher RV greyscale

RV greyscale outperformed other cardiac chamber measurements

Original publication

Survival following cardiac arrest is associated with lower spontaneous echo contrast of cardiac chamber blood. A retrospective analysis of echocardiograms from a large cardiac arrest study. Resuscitation. Published 17 July 2025. doi:10.1016/j.resuscitation.2025.110720

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.