A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE)
Authors' conclusion
Variable evidence exists to support the clinimetric properties of the CONCISE measurement instruments.
Study context
- Population
- Adults ≥ 18 years with or recovering from critical illness; CONCISE measurement instruments
- Participants
- 12,308 adults · 47 studies
- Outcome
- Clinimetric properties of the CONCISE measurement instruments
Methodological detailsCOSMIN checklist, modified GRADE certainty rating, narrative synthesis, 4 databases searched from inception to December 2022; 4316 studies screened
- COSMIN checklist
- Modified GRADE certainty rating
- Narrative synthesis
- 4 databases searched from inception to December 2022; 4316 studies screened
Pooled result
As reported in the abstract
Clinimetric properties
- Strongest clinimetric properties and certainty of evidence: SF-36 (Physical Component Score and Physical Functioning), sit-to-stand test, 6-m walk test, Barthel Index
- Less favourable results: Short Physical Performance Battery, Katz Index, handgrip strength
- Limited data: Lawson Instrumental Activities of Daily Living, Global Leadership Initiative on Malnutrition criteria
- Risk of bias ranged from inadequate to very good
- Certainty of evidence ranged from very low to high
Original publication
A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE). Crit Care. Published 20 November 2023. doi:10.
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