Pediatric anesthesia & critical care
Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review
Authors' conclusion
Tandem EBP/STs remain an emerging but incompletely standardized intervention in pediatric critical care.
Study context
- Population
- Critically ill children receiving tandem extracorporeal blood purification/support therapies (CRRT, therapeutic plasma exchange, ECMO)
Main finding
As reported in the abstract
- Tandem EBP/ST increasingly used in children with sepsis-induced multiple organ failure, acute liver failure, and thrombocytopenia-associated multiple organ dysfunction syndrome
- Benefits: reduced procedural downtime, optimized vascular access, enhanced therapeutic efficiency
- Limitations: off-label use, widely variable protocols, no child-specific guidelines
Safety
Complications of tandem therapy
- Increased risk of complications such as hypocalcemia and hemodynamic instability
Original publication
Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review. Crit Care Med. Published 21 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →