Liberation from continuous renal replacement therapy due to renal recovery in adults and children: a literature review and Delphi consensus on clinical practice
Authors' conclusion
UOP without the use of diuretics prior to liberation from CRRT was the most commonly reported predictor for successful CRRT liberation.
Study context
- Population
- Adults and children with AKI receiving continuous renal replacement therapy (CRRT)18 studies
- Participants
- 3,357 vs 939
- Comparison
- Adults vs Children
- Adultsn = 3,357
- Childrenn = 939
- Outcome
- Predictors of successful liberation from CRRT
Methodological detailstwo-round modified Delphi process, Statements with over 75% of respondents rating them at least 3 on a 5-point Likert scale classified as clinically relevant practice points
- Two-round modified Delphi process
- Statements with over 75% of respondents rating them at least 3 on a 5-point Likert scale classified as clinically relevant practice points
Recommendations
As reported in the abstract
Predictors of successful CRRT liberation
Adults: Urine output (UOP) thresholds correlating with successful outcomes
> 60 mL/hr or > 400 mL/day
Children: UOP within 6 h before liberation a reliable predictor
> 0.5 mL/kg/hr
Original publication
Liberation from continuous renal replacement therapy due to renal recovery in adults and children: a literature review and Delphi consensus on clinical practice. Crit Care. Published 8 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →